AONYS® drug delivery technology

AONYS® drug delivery technology

AONYS® is a mix of lipidic components that spontaneously assemble into a water-in-oil microemulsion. The active agent is solubilized in the aqueous phase of the microemulsion, within reverse micelles of 4 to 5 nm in diameter. AONYS® allows the administration of low...
Drug to treat neurodegenerative diseases

Drug to treat neurodegenerative diseases

NanoLithium® (NP03) is a disease-modifying nano dose formulation of lithium citrate in an AONYS® reverse microemulsion. NP03 allows the delivery of lithium citrate to all tissues with a strong therapeutic efficacy at doses two orders of magnitude lower than those used...
Treatment of Huntington’s disease

Treatment of Huntington’s disease

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease due to CAG expansion in the huntingtin gene. Through a screening on polyQ-hHTT aggregation in HeLa cells, F. Maschat (CNRS Montpellier) recently identified an inhibitory 23aa peptide (P42)...
Huntington’s disease

Huntington’s disease

HUNTINGTON’S DISEASE, HD Huntington’s Disease (HD) is a fatal autosomal dominant progressive neurodegenerative disease, characterized by progressive motor impairment (involuntary movements, chorea, dyskinesia, dystonia), psychiatric disturbances (change in mood,...